Menü
Fiókom
 
  • MagyarEnglish
KOSÁR
Szállítási díj 100 Ft
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte
GAL Biocurcumin+ Forte

GAL Biocurcumin+ Forte

Article No. :
GYKGABCF06001
7 590 Ft

Micronized turmeric extract in absorption enhancing matrix

GAL Biocurcumin+ Forte

The absorption of the active substances of turmeric into the blood circulation is very limited. We created this product to address this issue.

An extract of black pepper, BioPerine® can increase the absorption of curcuminoids by up to 2000%. In addition, a new, patented turmeric extract, Bio-Curcumin®(BCM-95®) contains micronized curcuminoids combined with turmeric essential oil, and it is 6 times more effective even than the black pepper extract.

The active substance of ginger called gingerol also enhances the absorption of curcumin, moreover, its effect is similar to that of curcumin, especially when used together with ginger essential oils.

The turmeric extract standardized for turmerones also significantly enhances  the absorption of curcumin. Our product is infused with this combination!

Recommended consumption is 1 capsule per day with meal.

Main category >Products
To Favourites
Recommend
Comparison
Print
Question about the product
Details
Info
Ingredients
Details

Turmeric root has been used for at least 4,000 years in India and its Asiatic neighbours. It is one of their most highly reputed herbs and also a spice found in almost all Indian cuisine. It is worthy to note that in India, many common diseases occur remarkably less frequently, including tumor diseases. Relative to this it is even more surprising as their consumption levels of sugar, refined carbohydrates and milk are high, factors which are known to increase the risk of these illnesses in the West. High turmeric consumption is traditionally thought to explain the lower occurrence of diseases. As a consequence this plant attracted significant scientific attention and study and analysis. The outcome of these investigations suggested that it was very effective in in vitro and animal studies relative to cases of cancer, arthritic and nervous system conditions and other health problems.

Hitherto, studies performed on people (human clinical studies) only found it useful in cases of intestinal conditions, because of the traditional limitations enacted by orally administered turmeric and curcumin (the main active substance). These substances could not pass from the intestinal system to the blood, through ingestion. Whereas, to be effective in the body as a whole, the active substance has to successfully cross the so-called blood-brain barrier. Therefore it has to get into the blood stream, to be effective in the digestive system, the brain, the nervous system etc. Historic observations suggested that to achieve absorption into the bloodstream, turmeric extracts with high curcumin content (95%) were administered in the form of injections, thus entering the blood circulation system directly. Modern innovation has furnished an increasing number of solutions to deliver orally taken curcumin into the bloodstream efficiently. Many of the products were found effective in a myriad of conditions (Arthritis, Alzheimer’s, Depressions, Digestive and Intestinal disorders etc.). But! In the main, these proffered solutions were compromised by harmful side effects. A consequence of the inclusion of differing absorption additives (e.g. polysorbate emulsions or soy proteins). Many of which increase the permeability of the intestinal walls, which is not good.

Through the implementation of modern technologies and methodologies, the oral delivery system has greatly benefitted over the years from research, discovery and the development of natural and healthy solutions. These natural remedies are carefully selected and utilised in our product. This expertise and finesse is what makes our product unique.

The active substances of turmeric

The better researched active substances are Curcuminoids (of which there are 3 types). The spice itself contains approx. 3% of these. The majority of research studies related to turmeric are focusing on curcuminoids (and among these, primarily on curcumin). It also has to be mentioned that turmeric root contains -1-2% of essential oils, some constituents of which - called turmerons - have strong anti-inflammatory and antioxidant effects. Besides having similar and synergistic effects with curcuminoids, they significantly increase the absorption rate of orally administered curcuminoids into the bloodstream. Conventional turmeric extracts, standardized for curcumin, do not contain turmerons present in essential oils.

The issue of absorption and its practical implications

The following natural and healthy techniques are available to improve absorption rate without adverse effects:

A pungent active ingredient of peppers and chili, piperine increases the blood supply of the intestine system, which in itself helps absorption; on the other hand, it decreases the activity of the liver enzyme P450, which would break down curcumin into ineffective degradation products. In a human clinical trial, the group that took curcumin together with a black pepper extract with high piperine content - patented under the name of BioPerine® - had 20 times higher blood curcumin levels compared to the other group taking the same amount of curcumin without BioPerine®. In addition, BioPerine® helps curcumin to cross the blood-brain barrier, thus it can perform its beneficial effects on the brain and the nervous system. Similarly to piperine, gingerols extracted from ginger increase the bioavailability of curcumin through similar mechanisms, although this was not yet confirmed in clinical trials, only in animal studies. Meanwhile, it was clinically confirmed that ginger extracts standardized for gingerols have a strong anti-inflammatory effect, with similar mechanism to that of curcumin. Historic research discovered, that in the ancient Indian medicine system, ayurveda, turmeric was combined over millennia with a preparation that helped absorption, called “trikatu”, which contains black pepper, long pepper and ginger, that is, piperine and gingerol.

A better and more most natural method has been developed recently:

Curcuminoids are mixed with a special version (high aromatic turmeron content, obtained without heat or chemical treatment) of the previously mentioned turmeric essential oil, then this special essential oil - curcuminoid complex is micronized, thus resulting in the production of a full-spectrum extract. This was patented under the names BioPerine® and BCM-95®. By comparing this with the piperine-lecithine-curcumin complex (the method used previously to promote absorption), it was determined that employing this method generated a 6-fold plus increase in the amount of curcumin entering the bloodstream of the study participants. Allied to this; is the benefit of the antioxidant and anti-inflammatory effects of the turmeron constituents of turmeric essential oils.

The extraordinary effects of BioCurcumin® have recently been proved in patients with Alzheimer’s disease, Rheumatoid Arthritis and Osteoarthritis. This demonstrates that the substance really entered the bloodstream (and thus, the joints as well), moreover, relative to the Alzheimer’s disease outcome it must have crossed the blood-brain barrier to enter the brain (Alzheimer).

1g of BioCurcumin® increases blood curcumin levels more than a 12g of traditional extract with high (95%) curcuminoid content, complemented with a high-fat diet with slow transit time that is favorable in terms of absorption.

Effects already confirmed by human clinical trials

Reducing and removing arthritic problems

A study in 2012 targeted a group of patients suffering from moderate rheumatic pain were divided into two trials. In group one each received 2×50mg strong anti-flammatory and analgesic medication containing the active substance diclofenac. Group two of the patients received 2×500mg BioCurcumin®. Patients who received BioCurcumin® experienced more significant improvement in their status and more pain relief compared to the group taking the strong medication.

It was noteworthy to observe that while the medication has a direct pain reducing effect, the pain reducing effect of BioCurcumin® can only be explained by an improvement in the cause of the problem. In another study in 2011, the efficacy of a preparation comprising BioCurcumin® and BosPure® incense extract was confirmed in patients suffering from osteoarthritic pain.

Easing depression

In a study in 2014, a group of patients with depression took 500mg Bio-Curcumin® daily for 6 weeks, which resulted in a 62.5% improvement measured on the Hamilton-scale. This was similar to the improvement achieved in the patient group taking antidepressants. The patient group taking both Bio-Curcumin® and antidepressants showed even more, 77.8% improvement.

Managing Alzheimer’s disease

In a study in 2008, daily 1g Bio-Curcumin® improved the state of patients with Alzheimer’s disease. It significantly decreased the amount of beta-amyloid plaques in the brain, which cause the disease; therefore it was observed that not only could it relieve the symptoms but might also reverse them.

Research studies concentrating on Bio-Curcumin® continue... It has been proved to be effective in in vitro and animal studies against urogenital diseases and breast and prostate cancer, and also that it helps the detoxifying function of the liver.

Other effects of curcumin, confirmed in human studies

It greatly reduces general inflammation in the body, the level of CRP, triglycerides and cholesterol, pain, lipid peroxidation, blood pressure, edema, depression, the risk of a number of tumor diseases, and the occurrence and symptoms of gastric or colorectal ulcers. In addition, it is a very strong antioxidant, and it also increases insulin sensitivity.

It has to be noted that, Bio-Curcumin® in itself elevates blood curcumin levels highly effectively, and it can cross the blood-brain barrier as the above mentioned studies demonstrate clearly. We further increased its effectivity, as we have combined it with other methods to help absorption. As an extra to Bio-Curcumin®, our product is infused with large amounts of turmeric essential oil, ginger extract, ginger essential oil and BioPerine® welcome additions. We are not aware of any other product that combines all of the available methods to promote the absorption of turmeric.

Recommended dosage

Pills should always be taken during meals. Maximum 2 pills per meal. If you are susceptible to reflux, you may experience unpleasant sensations when taking the pill at the end of the meal, thus we recommend taking it at the beginning of the meal instead, together with the first bites and with some liquid.

For gastrointestinal problems or to prevent them, it may be sufficient to consume large amounts of turmeric, however, 1 pill per day during a meal is even more effective.

In case of depression, we recommend taking 1-2 pills daily.

For arthritic problems, it is best to take 3-4 pills daily for a month, which can be reduced to 1-2 pills per day when the symptoms improve.

In case of severe conditions (e.g. tumor diseases or Alzheimer’s), 3-6 capsules are recommended daily.

Disclaimer: Pursuant to the regulations by the European Union also effective in Hungary, dietary supplements are food products, the purpose of which is to supplement conventional diet, and which contain nutrients or other substances - separately or in combination - with nutritional or physiological effect. According to the official statement, these products are not medications, have no healing effect, and are not suitable for treating or preventing diseases. GAL VitalSynergyTech Kft. respects the provisions of EszCsM Decree 37/2004 (IV. 26.) – which is a legal source for the aforementioned – as well as the requirements stipulated by the Hungarian Competition Authority. We hereby represent that our articles about the agents contained in our products have been assembled solely on the basis of the latest independent and relevant research, upon in-depth study of their interrelations, and serve the purpose of presenting them with the aim of providing information to our receptive and inquisitive Readers. These texts do not aim at boosting sales, and do not encourage for the purchase of our products. The only reason for our Customers to honor us with their recurring orders should be the fact that they have experienced the beneficial effects of GAL products. This is what we believe in, this is what we work for. 

 

References:
1. United States Department of Agriculture: „Sugar: World Markets and Trade” Foreign Agricultural Service, November 2013
2. The Food and Agriculture Organization of the United Nations (FAO): Milk Production in India and the United States from 2005 to 2011; FAO-STAT. June 4, 2013. (http://faostat.fao.org)
3. V. Mohan, G. Radhika, P. Vijayalakshmi, V. Sudha: Can the diabetes/cardiovascular disease epidemic in India be explained, at least in part, by excess refined grain (rice) intake? Indian J Med Res 131, March 2010, pp 369-372
4. Bengmark, S.: Plant-derived Health-Effects of Turmeric and Curcumenoids Kuwait Medical Journal 2006, 38 (4): 267-275
5. Shiyou Li, Wei Yuan, Guangrui Deng, Ping Wang, Peiying Yang, Bharat B. Aggarwal: Chemical Composition and Product Quality Control of Turmeric (Curcuma longa L.) Pharmaceutical Crops, 2011, 2, 28-54
6. Srinivas L, Shalini VK, ShylajaM. Turmerin: a water soluble antioxidant peptide from turmeric [Curcuma Longa]. Archem Biochem Biophys. 1992 Feb 1; 292 (2): 617-23.
7. http://examine.com/supplements/Curcumin/
8. Reji Kizhakkedath: Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. Molecular Medicine Reports, DOI: 10.3892/mmr.2013.1661
9. Chandran B, Goel A. A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis. Phytother Res. March 9, 2012 doi: 10.1002/ptr.4639
10. Antony B, Kizhakedath R, Benny M, Kuruvilla BT. Clinical Evaluation of a herbal product (Rhulief™) in the management of knee osteoarthritis. Abstract 316. Osteoarthritis Cartilage. 2011;19(S1):S145-S146.
11. Baum L et al. Six-Month Randomized Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients with Alzheimer’s Disease. Journal of Clinical Psychopharmacology. Vol 28, Number 1, Feb 2008 pg 110-114
12. Belcaro et al: Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. 2010 Dec;15(4):337-44.
13. Garcea et al: Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5.
14. Preetha Anand, Ajaikumar B. Kunnumakkara, Robert A. Newman, and Bharat B. Aggarwal: Bioavailability of Curcumin: Problems and Promises Mol. Pharmaceutics, 2007, 4 (6), 807-818• DOI: 10.1021/mp700113r
15. Shaiju et al: Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects Cancer Epidemiol Biomarkers Prev June 2008 17; 1411
16. Singh et al: Piperine : A Bioenhancer International Journal of Pharmacy Research and Technology 2011 1(1) 01-05
17. Unibar Corporation: CurQnetic™ Bioavailability Studies (http://unibarcorp.com/research)
18. Khajuria és et al (2003) In-house study for a patent work
19. Wigler I, Grotto I, Caspi D, Yaron M: The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarth Cartilage. 2003 Nov;11(11):783-9.
20. Grzanna R, Lindmark L, Frondoza CG: Ginger--an herbal medicinal product with broad anti-inflammatory actions. J Med Food. 2005 Summer;8(2):125-32.
21. Antony et al: A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95®CG (Biocurcumax™), A Novel Bioenhanced Preparation of Curcumin Indian J Pharm Sci. 2008 Jul-Aug; 70(4): 445–449.
22. Grant KL, Schneider CD. Turmeric. Am J Health-Syst Pharm 2000; 57:1121-1122.
Info
Mire használható?
Skin, Bone, Gut, Vascular system, Pain, Tooh, losing weight, Inflammation, Nervous system, Immune system, Joint, Eyes health, Liver, Detoxification, Headache, Hormon balance, Thyroid, Cartilage, Stress, Intellectual functions, Pregnancy, Blood sugar, Blood pressure
Ingredients

WebShop System